Is It Possible To Estimate the Enantioselectivity of a Chiral Catalyst from Its Racemic Mixture?
Author:
Affiliation:
1. Laboratoire de Synthèse Asymétrique (UMR 8075), Institut de Chimie Moléculaire et des Matériaux d'Orsay, Université Paris-Sud, 91405 Orsay, France, and Process Research, Merck & Co., Inc., Rahway, New Jersey 07065
Publisher
American Chemical Society (ACS)
Subject
Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis
Link
https://pubs.acs.org/doi/pdf/10.1021/ja0300315
Reference21 articles.
1. New screening methodologies or combinatorial chemistry applied to asymmetric catalysts
2. High-Throughput Strategies for the Discovery of Catalysts
3. New Methods for the High-Throughput Screening of Enantioselective Catalysts and Biocatalysts
4. Some approaches rely on the addition of a suitable chiral additive.5-7The efficiency of a catalyst for kinetic resolution can be estimated from the racemic catalyst, as recently established.8
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