Design, Synthesis, and Biological Evaluation of 1,2,3,7-Tetrahydro-6H-purin-6-one and 3,7-Dihydro-1H-purine-2,6-dione Derivatives as Corticotropin-Releasing Factor1 Receptor Antagonists-Reference-Cited by-同舟云学术

Design, Synthesis, and Biological Evaluation of 1,2,3,7-Tetrahydro-6H-purin-6-one and 3,7-Dihydro-1H-purine-2,6-dione Derivatives as Corticotropin-Releasing Factor1 Receptor Antagonists

Published:2004-08-07 Issue:19 Volume:47 Page:4741-4754
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Hartz Richard A.¹,Nanda Kausik K.¹,Ingalls Charles L.¹,Ahuja Vijay T.¹,Molski Thaddeus F.¹,Zhang Ge¹,Wong Harvey¹,Peng Yong¹,Kelley Michelle¹,Lodge Nicholas J.¹,Zaczek Robert¹,Gilligan Paul J.¹,Trainor George L.¹

Affiliation:

1. Discovery Chemistry, Neuroscience Biology, and Metabolism and Pharmacokinetics, Bristol-Myers Squibb Company, Pharmaceutical Research Institute, 5 Research Parkway, Wallingford, Connecticut 06492

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm049787k

Reference43 articles.

1. HUMORAL HYPOTHALAMIC CONTROL OF ANTERIOR PITUITARY: A STUDY WITH COMBINED TISSUECULTURES

2. THE RELEASE OF CORTICOTROPHIN BY ANTERIOR PITUITARY TISSUE IN VITRO

3. Characterization of a 41-Residue Ovine Hypothalamic Peptide That Stimulates Secretion of Corticotropin and β-Endorphin

4. Characterization of rat hypothalamic corticotropin-releasing factor.

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