In Situ Biofabrication of Microbial Cellulose Capsules Carrying Cubosomes: Toward Colon Targeted Multidrug Delivery

Author:

Ferreira Filipe V.1ORCID,Ezazi Nazanin Z.23,Otoni Caio G.4ORCID,Aguiar Ana Carolina5,Bianchi Jhonatan R. O.5,Lopes João H.6,dos Santos Danilo M.1ORCID,Greca Luiz G.78ORCID,Barud Hernane S.9ORCID,Santos Hélder A.210ORCID,Rojas Orlando J.711ORCID,Mattoso Luiz Henrique Capparelli1ORCID

Affiliation:

1. Embrapa Instrumentation, Nanotechnology National Laboratory for Agriculture (LNNA), 13561-206 São Carlos, SP, Brazil

2. Drug Research Program, Division of Pharmaceutical Chemistry and Technology, Faculty of Pharmacy, University of Helsinki, Helsinki 00100, Finland

3. Department of Health Technology, Technical University of Denmark, Ørsteds Plads 345C, 2800Kgs. Lyngby, Denmark

4. Graduate Program in Materials Science and Engineering (PPGCEM), Department of Materials Engineering (DEMa), Federal University of São Carlos (UFSCar), 13565-905 São Carlos, SP, Brazil

5. School of Chemical Engineering, University of Campinas (UNICAMP), 13083-970 Campinas, SP, Brazil

6. Biomaterials and Biointerfaces Lab (BBLab), Department of Chemistry, Division of Fundamental Sciences (IEF), Aeronautics Institute of Technology (ITA), 12228-900 Sao Jose dos Campos-SP─Brazil

7. Department of Bioproducts and Biosystems, School of Chemical Engineering, Aalto University, FI-00076 Espoo, Finland

8. Cellulose & Wood Materials Laboratory, Swiss Federal Laboratories for Materials Science and Technology (EMPA), Dübendorf 8600, Switzerland

9. Biopolymers and Biomaterials Laboratory (BIOPOLMAT), University of Araraquara (UNIARA), Araraquara, 14801-340 São Paulo, Brazil

10. Department of Biomaterials and Biomedical Technology, University Medical Center Groningen, University of Groningen, Groningen 9713 AV, The Netherlands

11. Departments of Chemical & Biological Engineering, 2360 East Mall; Chemistry, 2036 Main Mall, and Wood Science, 2424 Main Mall, The University of British Columbia, Vancouver, BC V6T 1Z3, Canada

Funder

Canada Foundation for Innovation

Canada Research Chairs

Conselho Nacional de Desenvolvimento Cient?fico e Tecnol?gico

Funda??o de Amparo ? Pesquisa do Estado de S?o Paulo

Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior

Publisher

American Chemical Society (ACS)

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