O6-3-[131I]iodobenzylguanine: Improved Synthesis and Further Evaluation of a Potential Agent for Imaging of Alkylguanine-DNA Alkyltransferase
Author:
Affiliation:
1. Departments of Radiology, Biomedical Engineering, Pediatrics, Surgery, and Medicine, Duke University Medical Center, Durham, North Carolina 27710
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Pharmaceutical Science,Pharmacology,Biomedical Engineering,Bioengineering,Biotechnology
Link
https://pubs.acs.org/doi/pdf/10.1021/bc0341977
Reference42 articles.
1. Srivenugopal, K. S., Yuan, X.H., Friedman, H. S., and Ali-Osman, F. (1996) Ubiquitination-dependent proteolysis ofO6-methylguanine-DNA methyltransferase in human and murine tumor cells following inactivation withO6-benzylguanine or 1,3-bis(2-chloroethyl)-1-nitrosourea.Biochemistry35, 1328−1334.
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