DNA Topoisomerases as Targets for the Anticancer Drug TAS-103: Primary Cellular Target and DNA Cleavage Enhancement-Reference-Cited by-同舟云学术

DNA Topoisomerases as Targets for the Anticancer Drug TAS-103: Primary Cellular Target and DNA Cleavage Enhancement

Published:1999-11-01 Issue:47 Volume:38 Page:15573-15579
ISSN:0006-2960
Container-title:Biochemistry
language:en
Short-container-title:Biochemistry

Author:

Wilson Byl Jo Ann¹,Fortune John M.¹,Burden D. Andrew¹,Nitiss John L.¹,Utsugi Teruhiro¹,Yamada Yuji¹,Osheroff Neil¹

Affiliation:

1. Departments of Biochemistry and Medicine (Hematology), Vanderbilt University School of Medicine, Nashville Tennessee 37232-0146, Department of Molecular Pharmacology, St. Jude Children's Research Hospital, Memphis, Tennessee 38101, and Taiho Pharmaceutical Co., Ltd., Hanno Research Center, Hanno-City, Saitama, 357, Japan

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/bi991791o

Reference62 articles.

1. Antitumor Activity of a Novel Quinoline Derivative, TAS-103, with Inhibitory Effects on Topoisomerases I and II

2. In vitroAntitumor Activity of TAS-103, a Novel Quinoline Derivative That Targets Topoisomerases I and II

3. A Dual Topoisomerase Inhibitor, TAS-103, Induces Apoptosis in Human Cancer Cells

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