A Unified and Quantitative Receptor Model for the Microtubule Binding of Paclitaxel and Epothilone
Author:
Affiliation:
1. Department of Chemistry,Emory University, Atlanta, Georgia 30322, Chiron Corp., Emeryville, California 94608, and Dip. Farmaco Chimico Tecnologico, University of Siena, 55-53100 Italy
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/ol990521v
Reference49 articles.
1. (a) Jordon, M. A.; Wilson, L. InTaxane Anticancer Agents; Georg, G. I., Chen, T. T., Ojima, I., Vyas, D. M., Eds.; ACS Symposium Series 583; American Chemical Society: Washington, DC, 1995; pp 138−153.
2. How does taxol stabilize microtubules?
3. Epothilone A and B—Novel 16-Membered Macrolides with Cytotoxic Activity: Isolation, Crystal Structure, and Conformation in Solution
4. Epothilons A and B: Antifungal and Cytotoxic Compounds from Sorangium cellulosum (Myxobacteria). Production, Physico-chemical and Biological Properties.
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