N- and C-Terminal Modifications of Nociceptin/Orphanin FQ Generate Highly Potent NOP Receptor Ligands-Reference-Cited by-同舟云学术

N- and C-Terminal Modifications of Nociceptin/Orphanin FQ Generate Highly Potent NOP Receptor Ligands

Published:2005-02-15 Issue:5 Volume:48 Page:1421-1427
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Guerrini Remo¹,Caló Girolamo¹,Lambert David G.¹,Carrá Giacomo¹,Arduin Marika¹,Barnes Tim A.¹,McDonald John¹,Rizzi Daniela¹,Trapella Claudio¹,Marzola Erika¹,Rowbotham David J.¹,Regoli Domenico¹,Salvadori Severo¹

Affiliation:

1. Department of Pharmaceutical Sciences and Biotechnology Center and Department of Experimental and Clinical Medicine, Section of Pharmacology and Neuroscience Centre, University of Ferrara, 44100 Ferrara, Italy, and University Department Cardiovascular Sciences (Pharmacology and Therapeutics Group), Clinical Division of Anaesthesia, Critical Care and Pain Management, Leicester Royal Infirmary, Leicester, LE1 5WW, U.K.

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm040106v

Reference41 articles.

1. Orphanin FQ: A Neuropeptide That Activates an Opioidlike G Protein-Coupled Receptor

2. Isolation and structure of the endogenous agonist of opioid receptor-like ORL1 receptor

3. Cox, B. M.; Chavkin, C.; Christie, M. J.; Civelli, O.; Evans, C.; Hamon, M. D.; Hoellt, V.; Kieffer, B.; Kitchen, I.; McKnight, A. T.; Meunier, J. C.; Portoghese, P. S. Opioid receptors.The IUPHAR Compendium of ReceptorCharacterization and Classification, 2nd ed.; IUPHAR Media Ltd: London, 2000; pp 321−333.

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