Novel 1,3-Disubstituted 8-(1-benzyl-1H-pyrazol-4-yl) Xanthines: High Affinity and Selective A2B Adenosine Receptor Antagonists-Reference-Cited by-同舟云学术

Novel 1,3-Disubstituted 8-(1-benzyl-1H-pyrazol-4-yl) Xanthines: High Affinity and Selective A2B Adenosine Receptor Antagonists

Published:2006-05-20 Issue:12 Volume:49 Page:3682-3692
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Kalla Rao V.¹,Elzein Elfatih¹,Perry Thao¹,Li Xiaofen¹,Palle Venkata¹,Varkhedkar Vaibhav¹,Gimbel Arthur¹,Maa Tennig¹,Zeng Dewan¹,Zablocki Jeff¹

Affiliation:

1. Department of Bioorganic Chemistry, Department of Drug Research and Pharmacological Sciences, CV Therapeutics Inc., 3172 Porter Drive, Palo Alto, California 94304

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm051268%2B

Reference30 articles.

1. Adenosine-receptor subtypes: their relevance to adenosine-mediated responses in asthma and chronic obstructive pulmonary disease

2. Adenosine in Bronchoalveolar Lavage Fluid in Asthma

3. Adenosine in exhaled breath condensate in healthy volunteers and in patients with asthma

4. Adenosine-Activated Mast Cells Induce IgE Synthesis by B Lymphocytes: An A2B-Mediated Process Involving Th2 Cytokines IL-4 and IL-13 with Implications for Asthma

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