A General Mechanism for Signal Propagation in the Nicotinic Acetylcholine Receptor Family-Reference-Cited by-同舟云学术

A General Mechanism for Signal Propagation in the Nicotinic Acetylcholine Receptor Family

Published:2019-12-06 Issue:51 Volume:141 Page:19953-19958
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Oliveira Ana Sofia F.¹²,Edsall Christopher J.³,Woods Christopher J.²³,Bates Phil⁴⁵,Nunez Gerardo Viedma⁵,Wonnacott Susan⁶,Bermudez Isabel⁷,Ciccotti Giovanni⁸⁹¹⁰^ORCID,Gallagher Timothy²^ORCID,Sessions Richard B.¹^ORCID,Mulholland Adrian J.²^ORCID

Affiliation:

1. School of Biochemistry, University of Bristol, Bristol BS8 1DT, United Kingdom

2. Centre for Computational Chemistry, School of Chemistry, University of Bristol, Bristol BS8 1TS, United Kingdom

3. Research Software Engineering, Advanced Computing Research Centre, University of Bristol, Bristol BS1 5QD, United Kingdom

4. Department of Computer Science, Faculty of Engineering, University of Bristol, Bristol BS8 1TR, United Kingdom

5. Oracle Corporation, Oracle Cloud Development Centre, Bristol BS2 2JJ, United Kingdom

6. Department of Biology and Biochemistry, University of Bath, Bath BA2 7AY, United Kingdom

7. Department of Biological and Medical Sciences, Oxford Brookes University, Oxford OX30BP, United Kingdom

8. Institute for Applied Computing “Mauro Picone” (IAC), CNR, Via dei Taurini 19, 00185 Rome, Italy

9. School of Physics, University College of Dublin UCD-Belfield, Dublin 4, Ireland

10. Università di Roma La Sapienza, Ple. A. Moro 5, 00185 Roma, Italy

Funder

Engineering and Physical Sciences Research Council

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/jacs.9b09055

Reference60 articles.

1. The structural basis of function in Cys-loop receptors

2. Emerging Molecular Mechanisms of Signal Transduction in Pentameric Ligand-Gated Ion Channels

3. The nicotinic acetylcholine receptor: a typical ‘allosteric machine’

4. Presynaptic nicotinic ACh receptors

5. Nicotinic ACh receptors as therapeutic targets in CNS disorders

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