Photoinduced DNA Cleavage Reactions by Designed Analogues of Co(III)−Bleomycin: The Metalated Core Is the Primary Determinant of Sequence Specificity
Author:
Affiliation:
1. Department of Chemistry and Biochemistry, University of California, Santa Cruz, California 95064
Publisher
American Chemical Society (ACS)
Subject
Inorganic Chemistry,Physical and Theoretical Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/ic9503139
Reference30 articles.
1. A clinical review of bleomycin—a new antineoplastic agent
2. The role of redox-active metals in the mechanism of action of bleomycin
3. Mechanisms of bleomycin-induced DNA degradation
4. Identification of a key structural feature of cobalt(III)-bleomycins: An exogenous ligand (e.g. Hydroperoxide) bound to cobalt
5. Cobalt-bleomycin DNA system. Evidence of DNA bound superoxo and .mu.-peroxo cobalt-bleomycin complexes
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