1. Institute for Research in Biomedicine, 08028-Barcelona, Spain, CIBER-BBN, Networking Centre on Bioengineering, Biomaterials and Nanomedicine, PCB, 08028-Barcelona, Spain, Department of Organic Chemistry, University of Barcelona, 08028-Barcelona, Spain, and School of Chemistry, University of KwaZulu-Natal, 4001 Durban, South Africa