Synthesis and Voltage-Clamp Studies of Methyl 1,4-Dihydro-2,6-dimethyl-5-nitro-4-(benzofurazanyl)pyridine-3-carboxylate Racemates and Enantiomers and of Their Benzofuroxanyl Analogues-Reference-Cited by-同舟云学术

Synthesis and Voltage-Clamp Studies of Methyl 1,4-Dihydro-2,6-dimethyl-5-nitro-4-(benzofurazanyl)pyridine-3-carboxylate Racemates and Enantiomers and of Their Benzofuroxanyl Analogues

Published:1999-04-03 Issue:8 Volume:42 Page:1422-1427
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Visentin Sonja¹,Amiel Pascale¹,Fruttero Roberta¹,Boschi Donatella¹,Roussel Christian¹,Giusta Laura¹,Carbone Emilio¹,Gasco Alberto¹

Affiliation:

1. Department of Scienza e Tecnologia del Farmaco, Facoltà di Farmacia, Università degli Studi di Torino, via P. Giuria 9, 10125 Torino, Italy, Department of Neuroscienze, Unità di ricerca INFM, Università degli Studi di Torino, Corso Raffaello 30, 10125 Torino, Italy, and ENSSPICAM, University Aix Marseille III, Av. Escadrille Normandie Niemen, F-13397 Marseille Cedex 20, France

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm980623b

Reference22 articles.

1. Ca2+ channel ligands: Structure-function relationships of the 1,4-dihydropyridines

2. 1,4-Dihydropyridines: Effects of Chirality and Conformation on the Calcium Antagonist and Calcium Agonist Activities

3. Calcium Entry Blockers and Activators: Conformational and Structural Determinants of Dihydropyrimidine Calcium Channel Modulators

4. Benzofurazanyl- and benzofuroxanyl-1,4-dihydropyridines: synthesis, structure and calcium entry blocker activity

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