1. Department of Biotechnology, Delft University of Technology, Julianalaan 136, 2628BL Delft, The Netherlands, Department of Biotechnology, University of the Free State, Bloemfontein 9300, South Africa, Department of Organic and Inorganic Chemistry, University of Oviedo, Calle Julián Clavería 8, 33006 Oviedo, Spain, and Firmenich SA, Corporate R&D, Route des Jeunes 1, CH-1211 Geneva, Switzerland