On Terminal Alkynes That Can React with Active-Site Cysteine Nucleophiles in Proteases

Author:

Ekkebus Reggy1,van Kasteren Sander I.1,Kulathu Yogesh2,Scholten Arjen34,Berlin Ilana1,Geurink Paul P.1,de Jong Annemieke1,Goerdayal Soenita34,Neefjes Jacques14,Heck Albert J. R.34,Komander David2,Ovaa Huib14

Affiliation:

1. Division of Cell Biology, The Netherlands Cancer Institute, Amsterdam, The Netherlands

2. Division of Protein and Nucleic Acid Chemistry, MRC Laboratory of Molecular Biology, Cambridge, United Kingdom

3. Biomolecular Mass Spectrometry and Proteomics, Bijvoet Centre for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, Netherlands

4. Netherlands Proteomics Centre, Utrecht, The Netherlands

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

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