Changes in Protein Dynamics of the DNA Repair Dioxygenase AlkB upon Binding of Fe2+ and 2-Oxoglutarate-Reference-Cited by-同舟云学术

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Changes in Protein Dynamics of the DNA Repair Dioxygenase AlkB upon Binding of Fe2+ and 2-Oxoglutarate

Published:2012-04-09 Issue:16 Volume:51 Page:3334-3341
ISSN:0006-2960
Container-title:Biochemistry
language:en
Short-container-title:Biochemistry

Author:

Bleijlevens Boris¹²,Shivarattan Tara¹,van den Boom Kim S.³,de Haan Annett²,van der Zwan Gert³,Simpson Pete J.¹,Matthews Steve J.¹

Affiliation:

1. Division of Molecular Biosciences, Faculty of Natural Sciences, Imperial College London, South Kensington Campus, London SW7 2AZ, U.K.

2. Department of Medical Biochemistry, Academic Medical Center, University of Amsterdam, Meibergdreef 15, 1105 AZ Amsterdam, The Netherlands

3. Biomolecular Analysis and Spectroscopy, LaserLab, Vrije Universiteit Amsterdam, De Boelelaan 1081, 1081 HV, The Netherlands

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/bi201699e

Reference28 articles.

1. Repairing DNA-methylation damage

2. Inhibition of 2-oxoglutarate dependent oxygenases

3. AlkB-mediated oxidative demethylation reverses DNA damage in Escherichia coli

4. Oxidative demethylation by Escherichia coli AlkB directly reverts DNA base damage

5. Human and bacterial oxidative demethylases repair alkylation damage in both RNA and DNA

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1. The Role of Key Amino Acids of the Human Fe(II)/2OG-Dependent Dioxygenase ALKBH3 in Structural Dynamics and Repair Activity toward Methylated DNA;International Journal of Molecular Sciences;2024-01-17

2. Functional characterisation of Fe (II) and 2OG‐dependent dioxygenase TcALKBH4 in the red flour beetle, Tribolium castaneum;Insect Molecular Biology;2023-07-18

3. Oleic Acid Dissolves cGAS–DNA Phase Separation to Inhibit Immune Surveillance;Advanced Science;2023-03-22

4. Dataset for Spectroscopic, Structural and Dynamic Analysis of Human Fe(II)/2OG-Dependent Dioxygenase ALKBH3;Data;2023-03-03

5. Conformational Dynamics of Human ALKBH2 Dioxygenase in the Course of DNA Repair as Revealed by Stopped-Flow Fluorescence Spectroscopy;Molecules;2022-08-04

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