Protease-Mediated Separation of Cis and Trans Diastereomers of 2(R,S)-benzyloxymethyl-4(S)-carboxylic Acid 1,3-Dioxolane Methyl Ester: Intermediates for the Synthesis of Dioxolane Nucleosides
Author:
Affiliation:
1. Department of Chemistry, McGill University, 801 Sherbrooke Street W, Montréal, Québec, Canada H3A 2K6, and BioChem Pharma, Inc., 275 Armand Frappier Boulevard, Laval, Québec, Canada H7V 4A7
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/jo990757c
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1. (±)-Dioxolane-T ((±)-1-[(2β,4β)-2-(hydroxymethyl)-4-dioxolanyl]thymine)
2. Inhibitory activities of herpes simplex viruses type 1 and 2 and human cytomegalovirus by stereoisomers of 2′-deoxy-3′-oxa-5(E)-(2-bromovinyl)uridines and their 4′-thio analogues.
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