Preactivated Oxazaphosphorines Designed for Isophosphoramide Mustard Delivery as Bulk Form or Nanoassemblies: Synthesis and Proof of Concept-Reference-Cited by-同舟云学术

Preactivated Oxazaphosphorines Designed for Isophosphoramide Mustard Delivery as Bulk Form or Nanoassemblies: Synthesis and Proof of Concept

Published:2014-12-23 Issue:2 Volume:58 Page:705-717
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Skarbek Charles¹,Lesueur Lea L.¹,Chapuis Hubert²,Deroussent Alain¹,Pioche−Durieu Catherine³,Daville Aurore¹,Caron Joachim²,Rivard Michael⁴,Martens Thierry⁴,Bertrand Jean-Rémi¹,Le Cam Eric³,Vassal Gilles¹,Couvreur Patrick²,Desmaele Didier²,Paci Angelo¹⁵

Affiliation:

1. Université Paris-Sud, Centre National de la Recherche Scientifique (CNRS), and Gustave Roussy Cancer Campus Grand Paris, Laboratoire de Vectorologie et Thérapeutiques Anticancéreuses, UMR 8203, Villejuif, France-94805

2. Université Paris-Sud, Institut Galien, UMR 8612, Châtenay-Malabry, France-92296

3. CNRS UMR8126, Université Paris Sud 11, Institut Gustave Roussy, Villejuif, France-94805

4. Université Paris Est Créteil, Institut de Chimie et des Matériaux Paris-Est (ICMPE), UMR 7182, Thiais, France-94320

5. Gustave Roussy Cancer Campus Grand Paris, Service Interdépartemental de Pharmacologie et d’Analyse du Médicament (SIPAM), Villejuif, France-94805

Funder

Agence Nationale de la Recherche

Fondation Gustave Roussy

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm501224x

Reference29 articles.

1. Oxazaphosphorines: new therapeutic strategies for an old class of drugs

2. Distribution of ifosfamide and metabolites between plasma and erythrocytes

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4. Design of New Oxazaphosphorine Anticancer Drugs

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