Kolliphor Surfactants Affect Solubilization and Bioavailability of Fenofibrate. Studies of in Vitro Digestion and Absorption in Rats-Reference-Cited by-同舟云学术

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Kolliphor Surfactants Affect Solubilization and Bioavailability of Fenofibrate. Studies of in Vitro Digestion and Absorption in Rats

Published:2015-03-06 Issue:4 Volume:12 Page:1062-1071
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Berthelsen Ragna¹,Holm René¹²,Jacobsen Jette¹,Kristensen Jakob³,Abrahamsson Bertil⁴,Müllertz Anette¹⁵

Affiliation:

1. Department of Pharmacy, University of Copenhagen, Copenhagen, Denmark

2. Biologics and Pharmaceutical Science, H. Lundbeck A/S, Valby, Denmark

3. Ferring Pharmaceuticals A/S, Copenhagen, Denmark

4. AstraZeneca Pharmaceutics, R&D, Mölndal, Sweden

5. Bioneer:FARMA, Department of Pharmacy, University of Copenhagen, Copenhagen, Denmark

Funder

Innovation Consortium Predicting Drug Absorption

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/mp500545k

Reference35 articles.

1. Strategies to Address Low Drug Solubility in Discovery and Development

2. Calculated Molecular Properties and Multivariate Statistical Analysis in Absorption Prediction

3. Mechanisms of Surfactant Effects on Drug Absorption

4. Entrapment by Cremophor EL decreases the absorption of paclitaxel from the gut

5. Evaluation of the Impact of Surfactant Digestion on the Bioavailability of Danazol after Oral Administration of Lipidic Self-Emulsifying Formulations to Dogs

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