Structure−Activity Relationships of (S,Z)-2-Aminopurine Methylenecyclopropane Analogues of Nucleosides. Variation of Purine-6 Substituents and Activity against Herpesviruses and Hepatitis B Virus

Author:

Chen Xinchao1,Kern Earl R.1,Drach John C.1,Gullen Elizabeth1,Cheng Yung-Chi1,Zemlicka Jiri1

Affiliation:

1. Department of Chemistry, Developmental Therapeutics Program, Barbara Ann Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, Michigan 48201-1379; Department of Pediatrics, The University of Alabama at Birmingham, Birmingham, Alabama 35294; Department of Biologic and Materials Sciences, School of Dentistry, University of Michigan, Ann Arbor, Michigan 48019-1078; and Department of Pharmacology, Yale University School of Medicine, New Haven, Connecticut 06510-8066

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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