Inactivation of O6-Alkylguanine-DNA Alkyltransferase. 1. Novel O6-(Hetarylmethyl)guanines Having Basic Rings in the Side Chain-Reference-Cited by-同舟云学术

Inactivation of O6-Alkylguanine-DNA Alkyltransferase. 1. Novel O6-(Hetarylmethyl)guanines Having Basic Rings in the Side Chain

Published:1998-12-01 Issue:26 Volume:41 Page:5265-5271
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

McElhinney R. Stanley¹,Donnelly Dorothy J.¹,McCormick Joan E.¹,Kelly Jane¹,Watson Amanda J.¹,Rafferty Joseph A.¹,Elder Rhoderick H.¹,Middleton Mark R.¹,Willington Mark A.¹,McMurry T. Brian H.¹,Margison Geoffrey P.¹

Affiliation:

1. University Chemical Laboratory, Trinity College, Dublin 2, Ireland, and CRC Section of Genome Damage and Repair, Paterson Institute for Cancer Research, Christie Hospital (NHS) Trust, Manchester M20 4BX, United Kingdom

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm9708644

Reference58 articles.

1. Importance of the DNA repair enzyme O6-alkyl guanine alkyltransferase (AT) in cancer chemotherapy

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