Novel Nitrogen Mustard-Armed Combi-Molecules for the Selective Targeting of Epidermal Growth Factor Receptor Overexperessing Solid Tumors: Discovery of an Unusual Structure−Activity Relationship-Reference-Cited by-同舟云学术

Novel Nitrogen Mustard-Armed Combi-Molecules for the Selective Targeting of Epidermal Growth Factor Receptor Overexperessing Solid Tumors: Discovery of an Unusual Structure−Activity Relationship

Published:2007-05-01 Issue:11 Volume:50 Page:2605-2608
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Rachid Zakaria¹,Brahimi Fouad¹,Qiu Qiyu¹,Williams Christopher¹,Hartley Janet M.¹,Hartley John A.¹,Jean-Claude Bertrand J.¹

Affiliation:

1. Cancer Drug Research Laboratory, Department of Medicine, Division of Medical Oncology, McGill University Health Center/Royal Victoria Hospital, Montreal, H3A 1A1, Quebec, Canada, Chemical Computing Group Inc., 1010 Sherbrooke Street West, Suite 910, Montreal, H3A 2R7, Québec, Canada, and Drug-DNA Interactions Research Group, Department of Oncology, UCL, Cancer Research UK, 91 Riding House Street, London W1W 7BS, U.K.

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm070144p

Reference15 articles.

1. hMSH3 overexpression and cellular response to cytotoxic anticancer agents

2. Synthesis of half-mustard combi-molecules with fluorescence properties: correlation with EGFR status

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