Statistical DoE Approach to the Removal of Palladium from Active Pharmaceutical Ingredients (APIs) by Functionalized Silica Adsorbents
Author:
Affiliation:
1. PhosphonicS Ltd., 44c Western Avenue, Milton Park, Abingdon, OX14 4RU, United Kingdom
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Physical and Theoretical Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/op5000336
Reference38 articles.
1. Large-Scale Applications of Transition Metal-Catalyzed Couplings for the Synthesis of Pharmaceuticals
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3. Bien, J. T.; Lane, G. C.; Oberholzer, M. R.Organometallics in Process Chemistry; Topics in Organometallic Chemistry;Springer, 2004; Volume6, p263.
4. Guideline on the specification limits for residues of metal catalysts of metal reagents,EMEA, Doc. Ref. EMEA/CHMP/SWP/4446/2000, 2008.
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