1. Burnham Institute for Medical Research, 10901 North Torrey Pines Road, La Jolla, California 92037, INFN, Laboratori Nazionali di Frascati, Via E. Fermi 40, 00044, Frascati, Italy, and Department of Environmental, Occupational and Social Medicine, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy