4-Amido-2-aryl-1,2,4-triazolo[4,3-a]quinoxalin-1-ones as New Potent and Selective Human A3 Adenosine Receptor Antagonists. Synthesis, Pharmacological Evaluation, and Ligand−Receptor Modeling Studies-Reference-Cited by-同舟云学术

4-Amido-2-aryl-1,2,4-triazolo[4,3-a]quinoxalin-1-ones as New Potent and Selective Human A3 Adenosine Receptor Antagonists. Synthesis, Pharmacological Evaluation, and Ligand−Receptor Modeling Studies

Published:2006-06-01 Issue:13 Volume:49 Page:3916-3925
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Lenzi Ombretta¹,Colotta Vittoria¹,Catarzi Daniela¹,Varano Flavia¹,Filacchioni Guido¹,Martini Claudia¹,Trincavelli Letizia¹,Ciampi Osele¹,Varani Katia¹,Marighetti Federico¹,Morizzo Erika¹,Moro Stefano¹

Affiliation:

1. Dipartimento di Scienze Farmaceutiche, Laboratorio di Progettazione, Sintesi e Studio di Eterocicli Biologicamente Attivi, Università di Firenze, Polo Scientifico, Via Ugo Schiff, 6, 50019 Sesto Fiorentino, Italy, Dipartimento di Psichiatria, Neurobiologia, Farmacologia e Biotecnologie, Università di Pisa, Via Bonanno, 6, 56126 Pisa, Italy, Dipartimento di Medicina Clinica e Sperimentale, Sezione di Farmacologia, Università di Ferrara, Via Fossato di Mortara 17-19, 44100 Ferrara, Italy, and Molecular...

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm060373w

Reference42 articles.

1. Adenosine receptors as therapeutic targets

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