In Vitro Approach to Assess the Potential for Risk of Idiosyncratic Adverse Reactions Caused by Candidate Drugs-Reference-Cited by-同舟云学术

In Vitro Approach to Assess the Potential for Risk of Idiosyncratic Adverse Reactions Caused by Candidate Drugs

Published:2012-05-31 Issue:8 Volume:25 Page:1616-1632
ISSN:0893-228X
Container-title:Chemical Research in Toxicology
language:en
Short-container-title:Chem. Res. Toxicol.

Author:

Thompson Richard A.¹,Isin Emre M.¹,Li Yan²,Weidolf Lars¹,Page Ken³,Wilson Ian³,Swallow Steve⁴,Middleton Brian⁵,Stahl Simone⁴,Foster Alison J.⁴,Dolgos Hugues¹,Weaver Richard⁶,Kenna J. Gerry⁴

Affiliation:

1. DMPK Innovative Medicine, AstraZeneca, Mölndal, 431 83, Sweden

2. Discovery DMPK, AstraZeneca, Wilmington, Delaware, United States

3. DMPK Innovative Medicine, AstraZeneca, Alderley Park, Macclesfield, Cheshire SK10 4TG, United Kingdom

4. Global Safety Assessment, AstraZeneca, Alderley Park, Macclesfield, Cheshire SK10 4TG, United Kingdom

5. Discovery Sciences, AstraZeneca, Alderley Park, Macclesfield, Cheshire SK10 4TG, United Kingdom

6. Discovery DMPK, AstraZeneca, Loughborough, Leicestershire LE11 5RH, United Kingdom

Publisher

American Chemical Society (ACS)

Subject

Toxicology,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/tx300091x

Reference72 articles.

1. First dose of potential new medicines to humans: how animals help

2. Trends in hospital admissions for adverse drug reactions in England: analysis of national hospital episode statistics 1998–2005

3. Adverse Drug Event Surveillance and Drug Withdrawals in the United States, 1969-2002

4. Adverse drug reactions: definitions, diagnosis, and management

5. Nonclinical development of biopharmaceuticals

Cited by 190 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Discovery, synthesis and SAR of 2-acyl-1-biarylmethyl pyrazolidines, dual orexin receptor antagonists designed as fast and short-acting sleeping drugs;Bioorganic & Medicinal Chemistry;2024-10

2. Control compounds for preclinical drug-induced liver injury assessment: Consensus-driven systematic review by the ProEuroDILI network;Journal of Hepatology;2024-05

3. Development of a Novel In Silico Classification Model to Assess Reactive Metabolite Formation in the Cysteine Trapping Assay and Investigation of Important Substructures;Biomolecules;2024-04-30

4. Application of Covalent Binding Body Burden in the HμREL Human Hepatocyte Coculture Model for Reactivity Risk Assessment of Metabolically Low Turnover Drugs;Chemical Research in Toxicology;2024-03-26

5. Development of a novelin silicoclassification model to assess reactive metabolite formation in the cysteine trapping assay and investigation of important substructures;2024-02-14