Tyrosine Kinase Inhibitors. 8. An Unusually Steep Structure−Activity Relationship for Analogues of 4-(3-Bromoanilino)-6,7-dimethoxyquinazoline (PD 153035), a Potent Inhibitor of the Epidermal Growth Factor Receptor-Reference-Cited by-同舟云学术

Tyrosine Kinase Inhibitors. 8. An Unusually Steep Structure−Activity Relationship for Analogues of 4-(3-Bromoanilino)-6,7-dimethoxyquinazoline (PD 153035), a Potent Inhibitor of the Epidermal Growth Factor Receptor

Published:1996-01-01 Issue:1 Volume:39 Page:267-276
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Bridges Alexander J.¹,Zhou Hairong¹,Cody Donna R.¹,Rewcastle Gordon W.¹,McMichael Amy¹,Showalter H. D. Hollis¹,Fry David W.¹,Kraker Alan J.¹,Denny William A.¹

Affiliation:

1. Parke-Davis Pharmaceutical Research, Division of Warner-Lambert Company, 2800 Plymouth Road, Ann Arbor, Michigan 48106-1047, and Cancer Research Laboratory, University of Auckland School of Medicine, Private Bag 92019, Auckland, New Zealand

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm9503613

Reference36 articles.

1. neu(c-erbB-2/HER2) and the Epidermal Growth Factor Receptor (EGFR) in Breast Cancer

2. Expression of epidermal growth factor receptor and proliferating cell nuclear antigen predicts response of esophageal squamous cell carcinoma to chemoradiotherapy

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