Amino Acid Phosphoramidate Monoesters of 3‘-Azido-3‘-deoxythymidine: Relationship between Antiviral Potency and Intracellular Metabolism
Author:
Affiliation:
1. Departments of Medicinal Chemistry and Microbiology, University of Minnesota, Minneapolis, Minnesota 55455
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm000260r
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1. Metabolism and mechanism of antiretroviral action of purine and pyrimidine derivatives
2. Pharmacokinetics of zidovudine phosphorylation in peripheral blood mononuclear cells from patients infected with human immunodeficiency virus
3. Long-Term Exposure to Zidovudine Affectsin Vitroandin Vivothe Efficiency of Phosphorylation of Thymidine Kinase
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