HCV NS5b RNA-Dependent RNA Polymerase Inhibitors: From α,γ-Diketoacids to 4,5-Dihydroxypyrimidine- or 3-Methyl-5- hydroxypyrimidinonecarboxylic Acids. Design and Synthesis-Reference-Cited by-同舟云学术

HCV NS5b RNA-Dependent RNA Polymerase Inhibitors: From α,γ-Diketoacids to 4,5-Dihydroxypyrimidine- or 3-Methyl-5- hydroxypyrimidinonecarboxylic Acids. Design and Synthesis

Published:2004-09-16 Issue:22 Volume:47 Page:5336-5339
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Summa Vincenzo¹,Petrocchi Alessia¹,Matassa Victor G.¹,Taliani Marina¹,Laufer Ralph¹,De Francesco Raffaele¹,Altamura Sergio¹,Pace Paola¹

Affiliation:

1. Departments of Medicinal Chemistry and Biochemistry IRBM-MRL Rome, Via Pontina, Km 30.600, 00040 Pomezia (Rome), Italy

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm0494669

Reference22 articles.

1. An Assay for Circulating Antibodies to a Major Etiologic Virus of Human Non-A, Non-B Hepatitis

2. Treatment of chronic hepatitis C with PEGylated interferon and ribavirin

3. Emerging therapies for hepatitis C virus infection

4. Hepatitis C Virus Infection

Cited by 107 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. N-Heterocycles as Promising Antiviral Agents: A Comprehensive Overview;Molecules;2024-05-10

2. Inhibiting HCMV pUL89-C Endonuclease with Metal-Binding Compounds;Journal of Medicinal Chemistry;2023-10-12

3. Targeting Metalloenzymes: The “Achilles’ Heel” of Viruses and Parasites;Pharmaceuticals;2023-06-19

4. Effects of natural polymorphisms in SARS-CoV-2 RNA-dependent RNA polymerase on its activity and sensitivity to inhibitors in vitro;Biochimie;2023-03

5. 4,5-Dihydroxypyrimidine Methyl Carboxylates, Carboxylic Acids, and Carboxamides as Inhibitors of Human Cytomegalovirus pUL89 Endonuclease;Journal of Medicinal Chemistry;2022-04-04