Design, Synthesis, and Evaluation of Tricyclic, Conformationally Constrained Small-Molecule Mimetics of Second Mitochondria-Derived Activator of Caspases-Reference-Cited by-同舟云学术

Design, Synthesis, and Evaluation of Tricyclic, Conformationally Constrained Small-Molecule Mimetics of Second Mitochondria-Derived Activator of Caspases

Published:2008-11-14 Issue:23 Volume:51 Page:7352-7355
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Zhang Bin¹,Nikolovska-Coleska Zaneta¹,Zhang Yan¹,Bai Longchuan¹,Qiu Su¹,Yang Chao-Yie¹,Sun Haiying¹,Wang Shaomeng¹,Wu Yikang¹

Affiliation:

1. State Key Laboratory of Bio-organic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Road, Shanghai 200032, China, and Comprehensive Cancer Center and Departments of Internal Medicine, Pharmacology, and Medicinal Chemistry, University of Michigan, 1500 E. Medical Center Drive, Ann Arbor, Michigan 48109

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm801146d

Reference26 articles.

1. Apoptosis in cancer

2. Apoptosis-based therapies

3. IAP family proteins---suppressors of apoptosis

4. IAP proteins: blocking the road to death's door

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