HIV-1 Reverse Transcriptase Structure with RNase H Inhibitor Dihydroxy Benzoyl Naphthyl Hydrazone Bound at a Novel Site-Reference-Cited by-同舟云学术

HIV-1 Reverse Transcriptase Structure with RNase H Inhibitor Dihydroxy Benzoyl Naphthyl Hydrazone Bound at a Novel Site

Published:2006-11-28 Issue:11 Volume:1 Page:702-712
ISSN:1554-8929
Container-title:ACS Chemical Biology
language:en
Short-container-title:ACS Chem. Biol.

Author:

Himmel Daniel M.¹,Sarafianos Stefan G.¹²,Dharmasena Sanjeewa³,Hossain Mohammed M.³,McCoy-Simandle Kessler³,Ilina Tatiana³,Clark Arthur D.¹,Knight Jennifer L.⁴,Julias John G.⁵,Clark Patrick K.⁵,Krogh-Jespersen Karsten⁴,Levy Ronald M.⁴,Hughes Stephen H.⁶,Parniak Michael A.³,Arnold Eddy¹

Affiliation:

1. Center for Advanced Biotechnology and Medicine and Department of Chemistry and Chemical Biology, Rutgers University, Piscataway, New Jersey 08854-5627

2. Current address, Christopher Bond Life Sciences Center, Department of Molecular Microbiology and Immunology, University of Missouri School of Medicine, Columbia, Missouri 65211-7310

3. Department of Medicine, Division of Infectious Diseases, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15261-0001

4. Department of Chemistry and Chemical Biology and BIOMAPS Institute for Quantitative Biology, Rutgers University, Piscataway, New Jersey 08854-8066

5. Basic Research Program, SAIC-Frederick, Inc., Frederick, Maryland 21702-1201

6. HIV Drug Resistance Program, NCI-Frederick, Building 539, Frederick, Maryland 21702-1201

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/cb600303y

Reference51 articles.

1. Mutations within the RNase H Domain of Human Immunodeficiency Virus Type 1 Reverse Transcriptase Abolish Virus Infectivity