Systems Toxicology: From Basic Research to Risk Assessment

Author:

Sturla Shana J.1,Boobis Alan R.2,FitzGerald Rex E.3,Hoeng Julia4,Kavlock Robert J.5,Schirmer Kristin6,Whelan Maurice7,Wilks Martin F.3,Peitsch Manuel C.4

Affiliation:

1. Department of Health Sciences and Technology, Institute of Food, Nutrition and Health, ETH Zürich, Schmelzbergstrasse 9, 8092 Zürich, Switzerland

2. Centre for Pharmacology & Therapeutics, Department of Medicine, Imperial College London, Hammersmith Campus, London W12 0NN, United Kingdom

3. Swiss Centre for Applied Human Toxicology, University of Basel, Klingelbergstrasse 61, CH-4056 Basel, Switzerland

4. Philip Morris International R&D, Philip Morris Products S.A., Quai Jeanrenaud 5, 2000 Neuchâtel, Switzerland

5. Office of Research and Development, U.S. Environmental Protection Agency 1200 Pennsylvania Avenue North West, Washington, DC 20460, United States

6. Environmental Toxicology, Eawag, Swiss Federal Institute of Aquatic Science and Technology, Überlandstrasse 133, 8600 Dübendorf, Switzerland

7. European Commission, DG Joint Research Centre, Institute for Health and Consumer Protection, Via E. Fermi, 2749, 21027 Ispra, Italy

Publisher

American Chemical Society (ACS)

Subject

Toxicology,General Medicine

Reference98 articles.

1. Toxicogenomics and systems toxicology: aims and prospects

2. Systems toxicology

3. A roadmap for the development of alternative (non-animal) methods for systemic toxicity testing

4. Directive 2010/63/EU of the European Parliament and of the Council of 22 September 2010 on the protection of animals used for scientific purposes,Official Journal of the European Union, L 276, pp33–78.

5. Regulation (EC) no 1223/2009 of the European Parliament and of the Council of 30 November 2009 on cosmetic products,Official Journal of the European Union, L 342, 22.12.2009, pp59–209.

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