1. Division of Biomedical Polymer Science, Institute for Comprehensive Medical Science, Fujita Health University, and Department of Medical Information Technology, Fujita Health University College, Toyoake, Aichi 470-1192, Japan, First Department of Internal Medicine, Nagoya University School of Medicine, Nagoya, Aichi 466-8550, Japan, and Department of Blood Transfusion Medicine, Nara Medical University, Kashihara, Nara 634-8522, Japan