A Tandem Enyne/Ring Closing Metathesis Approach to 4-Methylene-2-cyclohexenols: An Efficient Entry to Otteliones and Loloanolides
Author:
Affiliation:
1. Department of Chemistry, Indian Institute of Technology Bombay, Powai, Mumbai 400076, India
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/ol2029838
Reference38 articles.
1. Otteliones A and B: Potently Cytotoxic 4-Methylene-2-cyclohexenones from Ottelia alismoides
2. Incidentally, ottelione A (2) was identical to the compound named RPR112378 previously reported in the patent literature by a research group at Rhône-Poulenc Rorer (now Sanofi-Aventis); see:Leboul, J. Provost, J.French patent WO96/00205, 1996 [Chem. Abstr.1996,124,242296].
3. Three New Eudesmanolactones (=Eudesmanolides) from Camchaya loloana
4. Thermal rearrangement of 3-methylenespiro[5.6]dodeca-1,4,9-triene and spiro[5.6]dodeca-1,4,9-trien-3-one
5. An Improved Synthesis of 4-Methylene-2-cyclohexen-1-one
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