Discovery of trans-4-[1-[[2,5-Dichloro-4-(1-methyl-3-indolylcarboxamido)phenyl]acetyl]-(4S)-methoxy-(2S)-pyrrolidinylmethoxy]cyclohexanecarboxylic Acid: An Orally Active, Selective Very Late Antigen-4 Antagonist-Reference-Cited by-同舟云学术

Discovery of trans-4-[1-[[2,5-Dichloro-4-(1-methyl-3-indolylcarboxamido)phenyl]acetyl]-(4S)-methoxy-(2S)-pyrrolidinylmethoxy]cyclohexanecarboxylic Acid: An Orally Active, Selective Very Late Antigen-4 Antagonist

Published:2009-11-05 Issue:24 Volume:52 Page:7974-7992
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Muro Fumihito¹,Iimura Shin¹,Sugimoto Yuuichi¹,Yoneda Yoshiyuki¹,Chiba Jun¹,Watanabe Toshiyuki¹,Setoguchi Masaki¹,Iigou Yutaka²,Matsumoto Keiko¹,Satoh Atsushi¹,Takayama Gensuke¹,Taira Tomoe¹,Yokoyama Mika¹,Takashi Tohru¹,Nakayama Atsushi¹,Machinaga Nobuo¹

Affiliation:

1. R&D Division, Daiichi Sankyo Co., Ltd., 1-16-13 Kitakasai, Edogawa-ku, Tokyo 134-8630, Japan

2. Research Department, Daiichi Sankyo RD Associe Co., Ltd., 3-10-2 Kitashinagawa, Shinagawa-ku, Tokyo 140-0001, Japan

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm901154c

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