Nanomolar Small Molecule Inhibitors for αvβ6, αvβ5, and αvβ3 Integrins-Reference-Cited by-同舟云学术

Nanomolar Small Molecule Inhibitors for αvβ6, αvβ5, and αvβ3 Integrins

Published:2002-01-31 Issue:5 Volume:45 Page:1045-1051
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Goodman Simon L.¹,Hölzemann Günter¹,Sulyok Gábor A. G.¹,Kessler Horst¹

Affiliation:

1. Departments of Preclinical Oncology and Medicinal Chemistry, Merck KGaA, Frankfurterstr. 250, 64271 Darmstadt, Germany, and Institute for Organic Chemistry and Biochemistry, Technische Universität München, Lichtenbergstr. 4, 85747 Garching, Germany

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm0102598

Reference54 articles.

1. Integrins: Versatility, modulation, and signaling in cell adhesion

2. Monoclonal antibody characterization of two distant sites required for function of the central cell-binding domain of fibronectin in cell adhesion, cell migration, and matrix assembly.

3. Design of a potent and orally active nonpeptide platelet fibrinogen receptor (GPIIb/IIIa) antagonist

4. Non-Peptide Fibrinogen Receptor Antagonists. 2. Optimization of a Tyrosine Template as a Mimic for Arg-Gly-Asp

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