Cytotoxic Xanthones from Psorospermum molluscum from the Madagascar Rain Forest

Author:

Leet John E.1,Liu Xiaohong1,Drexler Dieter M.1,Cantone Joseph L.1,Huang Stella1,Mamber Stephen W.1,Fairchild Craig R.1,Hussain Raouf1,Newman David J.1,Kingston David G. I.1

Affiliation:

1. Bristol-Myers Squibb Company, Research & Development, Wallingford, Connecticut 06492, Natural Products Branch, Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, Maryland 20892, and Department of Chemistry, M/C 0212, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Complementary and alternative medicine,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Analytical Chemistry

Reference18 articles.

1. A recent report suggests that spp. ofPsorospermummay be better placed in the genusHarungana(family Hypericaceae), in: Stevens, P. F. Hypericaceae. InThe Families and Genera of Vascular Plants, Volume IX;Kubitzki, K., Ed.Springer: Berlin, 2007; pp194–201.

2. Use of an Aqueous Soluble Tetrazolium/Formazan Assay for Cell Growth Assays in Culture

3. Bruceantin, a new potent antileukemic simaroubolide from Brucea antidysenterica

4. SOS chromotest, a direct assay of induction of an SOS function in Escherichia coli K-12 to measure genotoxicity.

5. The Escherichia coli K-12 SOS chromotest agar spot test for simple, rapid detection of genotoxic agents

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