Design and Nuclear Magnetic Resonance (NMR) Structure Determination of the Second Extracellular Immunoglobulin Tyrosine Kinase A (TrkAIg2) Domain Construct for Binding Site Elucidation in Drug Discovery-Reference-Cited by-同舟云学术

Design and Nuclear Magnetic Resonance (NMR) Structure Determination of the Second Extracellular Immunoglobulin Tyrosine Kinase A (TrkAIg2) Domain Construct for Binding Site Elucidation in Drug Discovery

Published:2014-12-22 Issue:2 Volume:58 Page:767-777
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Shoemark Debbie K.¹,Williams Christopher²,Fahey Mark S.¹,Watson Judy J.¹,Tyler Sue J.¹,Scoltock Simon J.¹,Ellis Rosamund Z.²,Wickenden Elaine²,Burton Antony J.²,Hemmings Jennifer L.²,Bailey Christopher D.²,Dawbarn David,Jane David E.³,Willis Christine L.²,Sessions Richard B.⁴,Allen Shelley J.¹,Crump Matthew P.²

Affiliation:

1. School of Clinical Sciences, Level 2, Learning and Research, Southmead Hospital, Bristol BS10 5NB, United Kingdom

2. School of Chemistry, University of Bristol, Cantock’s Close, Bristol BS8 1TS, United Kingdom

3. School of Physiology & Pharmacology, University of Bristol, Medical Sciences Building, University Walk, Bristol BS8 1TD, United Kingdom

4. School of Biochemistry, University of Bristol, Medical Sciences Building, University Walk, Bristol BS8 1TD, United Kingdom

Funder

Alzheimer's Research UK

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm501307e

Reference38 articles.

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