Point-of-Care Testing of Benzene Metabolite S-Phenylmercapturic Acid Using Salt-Induced Phase Separation Combined with Nanoparticle-Based Surface-Enhanced Raman Spectroscopy

Author:

Wei Haiyan1,Zou Wei2,Feng Rui3,Liu Luyun4,Zhang Mengping2,Meng Xiao2,Chen Wenwen2,Jia Qiang1,Wang Cuijuan2ORCID

Affiliation:

1. Toxicology Research Center, Shandong Academy of Occupational Health and Occupational Medicine, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan 250000, China

2. Physical and Chemical Laboratory, Shandong Academy of Occupational Health and Occupational Medicine, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan 250000, China

3. Department of Radiation Oncology and Shandong Provincial Key Laboratory of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan 250000, China

4. Neck-Shoulder and Lumbocrural Pain Hospital of Shandong First Medical University, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan 250000, China

Funder

National Key Research and Development Program of China

Shandong First Medical University

Medical and Health Science and Technology Development Project of Shandong Province

Natural Science Foundation of Shandong Province

Clinical Medical Science and technology Innovation Plan of Jinan

Medical and Health Science Project of Hainan Province

Traditional Chinese Medicine Project of Shandong Province

Publisher

American Chemical Society (ACS)

Reference35 articles.

1. Benzene induces rapid leukemic transformation after prolonged hematotoxicity in a murine model

2. Handheld Device for Selective Benzene Sensing over Toluene and Xylene

3. Occupational Benzene Exposure and Lung Cancer Risk: A Pooled Analysis of 14 Case-Control Studies

4. Benzene. IARC Working Group on the Evaluation of Carcinogenic Risks to Humans; International Agency for Research on Cancer: Lyon (FR), 2018. (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, no. 120) available from: https://www.ncbi.nlm.nih.gov/books/NBK550157/.

5. National Institute for Occupational Safety and Health (NIOSH). Benzene. https://www.cdc.gov/niosh/npg/npgd0049.html.

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