Synthesis and Stereochemical Structure−Activity Relationships of 1,3-Dioxoperhydropyrido[1,2-c]pyrimidine Derivatives: Potent and Selective Cholecystokinin-A Receptor Antagonists-Reference-Cited by-同舟云学术

Synthesis and Stereochemical Structure−Activity Relationships of 1,3-Dioxoperhydropyrido[1,2-c]pyrimidine Derivatives: Potent and Selective Cholecystokinin-A Receptor Antagonists

Published:1997-10-01 Issue:21 Volume:40 Page:3402-3407
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Martín-Martínez Mercedes¹,Bartolomé-Nebreda José M.¹,Gómez-Monterrey Isabel¹,González-Muñiz Rosario¹,García-López M. Teresa¹,Ballaz Santiago¹,Barber Ana¹,Fortuño Ana¹,Del Río Joaquín¹,Herranz Rosario¹

Affiliation:

1. Instituto de Química Médica (CSIC), Juan de la Cierva 3, E-28006 Madrid, Spain, and Departamentos de Farmacología y Fisiología, Universidad de Navarra, Irunlarrea 1, E-31008 Pamplona, Spain

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm9703247

Reference47 articles.

1. CHOLECYSTOKININ: A HORMONE AND A NEUROTRANSMITTER

2. Biological actions of cholecystokinin

3. Distinct cholecystokinin receptors in brain and pancreas.

4. Two brain cholecystokinin receptors: implications for behavioral actions

5. Autoradiography of CCK receptors in the rat brain using [3H]Boc[Nle2831]CCK27–33 and [125I]bolton-hunter CCK8. Functional significance of subregional distributions

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