Potent Small-Molecule Binding to a Dynamic Hot Spot on IL-2
Author:
Affiliation:
1. Sunesis Pharmaceuticals, Inc. 341 Oyster Point Boulevard, South San Francisco, California 94080
Publisher
American Chemical Society (ACS)
Subject
Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis
Link
https://pubs.acs.org/doi/pdf/10.1021/ja0382617
Reference17 articles.
1. Inhibition of Protein−Protein Association by Small Molecules: Approaches and Progress
2. Protein–protein interfaces: mimics and inhibitors
3. Protein−Protein Interactions: Interface Structure, Binding Thermodynamics, and Mutational Analysis
4. A Hot Spot of Binding Energy in a Hormone-Receptor Interface
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