Synthesis and Antitumor Effect in Vitro and in Vivo of Substituted 1,3-Dihydroindole-2-ones-Reference-Cited by-同舟云学术

Synthesis and Antitumor Effect in Vitro and in Vivo of Substituted 1,3-Dihydroindole-2-ones

Published:2010-09-16 Issue:19 Volume:53 Page:7140-7145
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Christensen Mette K.¹,Erichsen Kamille D.¹,Trojel-Hansen Christina¹²,Tjørnelund Jette¹,Nielsen Søren J.¹,Frydenvang Karla³,Johansen Tommy N.³,Nielsen Birgitte³,Sehested Maxwell¹²,Jensen Peter B.¹,Ikaunieks Martins⁴,Zaichenko Andrei⁴,Loza Einars⁴,Kalvinsh Ivars⁴,Björkling Fredrik¹³

Affiliation:

1. TopoTarget A/S, Symbion, Fruebjergvej 3, DK-2100 Copenhagen, Denmark

2. Experimental Pathology Unit, National University Hospital, Biocentre, Ole Maaloes Vej 5, 2200 Copenhagen, Denmark

3. Department of Medicinal Chemistry, Faculty of Pharmaceutical Sciences, University of Copenhagen, Universitetsparken 2, DK-2100 Copenhagen, Denmark

4. Latvian Institute of Organic Synthesis, Aizkraules 21, Riga LV-1006, Latvia

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm100763j

Reference16 articles.

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2. Felding, J.; Pedersen, H. C.; Krog-Jensen, C.; Præstegaard, M.; Butcher, S. P.; Linde, V.; Coulter, T. S.; Montalbetti, C.; Uddin, M.; Reignier, S.Diphenyl Ox-indol-2-on Compounds and Their Use in the Treatment of Cancer. WO2005097107(A2), 2005.

3. JAUNDICE DUE TO OXYPHENISATIN

4. Liver damage induced by oxyphenisatin.

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