1. Department of Anesthesiology and Critical Care Medicine, Kochi Medical School, Nankoku-city, Kochi 783-8505, Japan; Department of Natural Products Chemistry, School of Pharmacy, Wenzhou Medical School, Wenzhou 325035, China; Department of Anesthesiology, First Affiliated Hospital of China Medical University, Nanjing North Road 55, Shengyang 110001, China; and Department of Medical Plant Development, Shenyang Pharmaceutical University, Wenhua Road 103, Shenyang 110015, China