A Small Molecule Inhibitor, 1,2,4,5-Benzenetetraamine Tetrahydrochloride, Targeting the Y397 Site of Focal Adhesion Kinase Decreases Tumor Growth
Author:
Affiliation:
1. Department of Surgery, UF Shands Cancer Center, Department of Pathology and Laboratory Medicine, and Department of Biochemistry and Molecular Biology, University of Florida, Gainesville, Florida 32610-0245
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm800483v
Reference23 articles.
1. The focal adhesion kinase
2. Identification of sequences required for the efficient localization of the focal adhesion kinase, pp125FAK, to cellular focal adhesions.
3. Direct interaction of v-Src with the focal adhesion kinase mediated by the Src SH2 domain.
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