Rational Design, Synthesis, and Structure−Activity Relationships of Aryltriazoles as Novel Corticotropin-Releasing Factor-1 Receptor Antagonists-Reference-Cited by-同舟云学术

Rational Design, Synthesis, and Structure−Activity Relationships of Aryltriazoles as Novel Corticotropin-Releasing Factor-1 Receptor Antagonists

Published:2005-02-04 Issue:5 Volume:48 Page:1540-1549
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Lowe Richard F.¹,Nelson Jodene¹,Dang Trunghau N.¹,Crowe Paul D.¹,Pahuja Anil¹,McCarthy James R.¹,Grigoriadis Dimitri E.¹,Conlon Paul¹,Saunders John¹,Chen ¹,Szabo Thomas¹,Chen Ta Kung¹,Bozigian Haig¹

Affiliation:

1. Department of Medicinal Chemistry, Department of Pharmacology and Lead Discovery, and Department of Preclinical Development, Neurocrine Biosciences Inc., 12790 El Camino Real, San Diego, California 92130

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm049339c

Reference27 articles.

1. Characterization of a 41-Residue Ovine Hypothalamic Peptide That Stimulates Secretion of Corticotropin and β-Endorphin

2. The rationale for corticotropin-releasing hormone receptor (CRH-R) antagonists to treat depression and anxiety

3. Molecular Properties of the CRF Receptor

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