Synthesis and in Vitro and in Vivo Evaluation of Phosphoinositide-3-kinase Inhibitors-Reference-Cited by-同舟云学术

Synthesis and in Vitro and in Vivo Evaluation of Phosphoinositide-3-kinase Inhibitors

Published:2010-10-13 Issue:1 Volume:2 Page:34-38
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Burger Matthew T.¹,Knapp Mark¹,Wagman Allan¹,Ni Zhi-Jie¹,Hendrickson Thomas¹,Atallah Gordana¹,Zhang Yanchen¹,Frazier Kelly¹,Verhagen Joelle¹,Pfister Keith¹,Ng Simon¹,Smith Aaron¹,Bartulis Sarah¹,Merrit Hanne¹,Weismann Marion¹,Xin Xiaohua¹,Haznedar Joshua¹,Voliva Charles F.¹,Iwanowicz Ed¹,Pecchi Sabina¹

Affiliation:

1. Global Discovery Chemistry/Oncology & Exploratory Chemistry, Novartis Institutes for Biomedical Research, 4560 Horton Street, Emeryville, California 94608, United States

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ml1001932

Reference12 articles.

1. The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism

2. Cellular Function of Phosphoinositide 3-Kinases: Implications for Development, Immunity, Homeostasis, and Cancer

3. High Frequency of Mutations of the PIK3CA Gene in Human Cancers

4. PTEN function: how normal cells control it and tumour cells lose it

5. Targeting the phosphoinositide 3-kinase pathway in cancer

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