The δ Opioid Receptor Agonist SNC80 Selectively Activates Heteromeric μ–δ Opioid Receptors-Reference-Cited by-同舟云学术

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The δ Opioid Receptor Agonist SNC80 Selectively Activates Heteromeric μ–δ Opioid Receptors

Published:2012-05-24 Issue:7 Volume:3 Page:505-509
ISSN:1948-7193
Container-title:ACS Chemical Neuroscience
language:en
Short-container-title:ACS Chem. Neurosci.

Author:

Metcalf Matthew D.¹,Yekkirala Ajay S.¹²,Powers Michael D.¹,Kitto Kelley F.²³,Fairbanks Carolyn A.²⁴³,Wilcox George L.²³⁵,Portoghese Philip S.¹²³

Affiliation:

1. Department of Medicinal Chemistry, University of Minnesota College of Pharmacy, Minneapolis, Minnesota, United States

2. Department of Pharmacology, University of Minnesota School of Medicine, Minneapolis, Minnesota, United States

3. Department of Neuroscience, University of Minnesota School of Medicine, Minneapolis, Minnesota, United States

4. Department of Pharmaceutics, University of Minnesota College of Pharmacy, Minneapolis, Minnesota, United States

5. Department of Dermatology, University of Minnesota School of Medicine, Minneapolis, Minnesota, United States

Publisher

American Chemical Society (ACS)

Subject

Cell Biology,Cognitive Neuroscience,Physiology,Biochemistry,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/cn3000394

Reference30 articles.

1. Probes for Narcotic Receptor Mediated Phenomena. 19. Synthesis of (+)-4-[(.alpha.R)-.alpha.-((2S,5R)-4-Allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl]-N,N-diethylbenzamide (SNC 80): A Highly Selective, Nonpeptide .delta. Opioid Receptor Agonist

2. Probes for Narcotic Receptor Mediated Phenomena. 23. Synthesis, Opioid Receptor Binding, and Bioassay of the Highly Selective δ Agonist (+)-4-[(αR)-α-((2S,5R)-4-Allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl]- N,N-diethylbenzamide (SNC 80) and Related Novel Nonpeptide δ Opioid Receptor Ligands

3. SNC 80 and Related δ Opioid Agonists

4. Heterodimerization of μ and δ Opioid Receptors: A Role in Opiate Synergy

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