Leaving Groups Prolong the Duration of 20S Proteasome Inhibition and Enhance the Potency of Salinosporamides-Reference-Cited by-同舟云学术

Leaving Groups Prolong the Duration of 20S Proteasome Inhibition and Enhance the Potency of Salinosporamides

Published:2008-10-22 Issue:21 Volume:51 Page:6711-6724
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Manam Rama Rao¹,McArthur Katherine A.¹,Chao Ta-Hsiang¹,Weiss Jeffrey¹,Ali Janid A.¹,Palombella Vito J.¹,Groll Michael¹,Lloyd G. Kenneth¹,Palladino Michael A.¹,Neuteboom Saskia T. C.¹,Macherla Venkat R.¹,Potts Barbara C. M.¹

Affiliation:

1. Nereus Pharmaceuticals, Inc., 10480 Wateridge Circle, San Diego, California 92121, Infinity Pharmaceuticals, 780 Memorial Drive, Cambridge, Massachusetts 02139, and Center for Integrated Protein Science at the Department Chemie, Lehrstuhl für Biochemie, Technische Universität München, Lichtenbergstrasse 4, Garching D-85747, Germany

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm800548b

Reference55 articles.

1. Proteasome Inhibitors in Cancer Therapy: Lessons from the First Decade

2. Proteasome Inhibitors in Cancer Therapy

3. Proteasome inhibitors: from research tools to drug candidates

4. THE UBIQUITIN SYSTEM

5. 20S Proteasome and Its Inhibitors: Crystallographic Knowledge for Drug Development

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