Discovery of 7-N-Piperazinylthiazolo[5,4-d]pyrimidine Analogues as a Novel Class of Immunosuppressive Agents with in Vivo Biological Activity-Reference-Cited by-同舟云学术

Discovery of 7-N-Piperazinylthiazolo[5,4-d]pyrimidine Analogues as a Novel Class of Immunosuppressive Agents with in Vivo Biological Activity

Published:2010-12-20 Issue:2 Volume:54 Page:655-668
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Jang Mi-Yeon¹,Lin Yuan²,De Jonghe Steven²,Gao Ling-Jie²,Vanderhoydonck Bart²,Froeyen Mathy¹,Rozenski Jef¹,Herman Jean²,Louat Thierry²,Van Belle Kristien²,Waer Mark³,Herdewijn Piet¹

Affiliation:

1. Laboratory of Medicinal Chemistry, Rega Institute for Medical Research, Katholieke Universiteit Leuven, Minderbroedersstraat 10, 3000 Leuven, Belgium

2. Interface Valorisation Platform (IVAP), Katholieke Universiteit Leuven, Kapucijnenvoer 33, 3000 Leuven, Belgium

3. Laboratory of Experimental Transplantation, Campus Gasthuisberg, Katholieke Universiteit Leuven, Herestraat 49, 3000 Leuven, Belgium

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm101254z

Reference40 articles.

1. T cell–directed therapies: lessons learned and future prospects

2. Current immunosuppressive agents: efficacy, side effects, and utilization

3. Newer Immunosuppressive Drugs

4. A new modality for immunosuppression: targeting the JAK/STAT pathway

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