Identification of NVP-BKM120 as a Potent, Selective, Orally Bioavailable Class I PI3 Kinase Inhibitor for Treating Cancer-Reference-Cited by-同舟云学术

Identification of NVP-BKM120 as a Potent, Selective, Orally Bioavailable Class I PI3 Kinase Inhibitor for Treating Cancer

Published:2011-08-26 Issue:10 Volume:2 Page:774-779
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Burger Matthew T.¹,Pecchi Sabina¹,Wagman Allan¹,Ni Zhi-Jie¹,Knapp Mark¹,Hendrickson Thomas¹,Atallah Gordana¹,Pfister Keith¹,Zhang Yanchen¹,Bartulis Sarah¹,Frazier Kelly¹,Ng Simon¹,Smith Aaron¹,Verhagen Joelle¹,Haznedar Joshua¹,Huh Kay¹,Iwanowicz Ed¹,Xin Xiaohua¹,Menezes Daniel¹,Merritt Hanne¹,Lee Isabelle¹,Wiesmann Marion¹,Kaufman Susan¹,Crawford Kenneth¹,Chin Michael¹,Bussiere Dirksen¹,Shoemaker Kevin¹,Zaror Isabel¹,Maira Sauveur-Michel¹,Voliva Charles F.¹

Affiliation:

1. Global Discovery Chemistry/Oncology & Exploratory Chemistry, Novartis Institutes for Biomedical Research, 4560 Horton Street, Emeryville, California 94608, United States

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ml200156t

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