Orally Active, Water-Soluble Antimalarial 3-Aryltrioxanes: Short Synthesis and Preclinical Efficacy Testing in Rodents-Reference-Cited by-同舟云学术

Orally Active, Water-Soluble Antimalarial 3-Aryltrioxanes: Short Synthesis and Preclinical Efficacy Testing in Rodents

Published:2002-07-30 Issue:18 Volume:45 Page:3824-3828
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Posner Gary H.¹,Jeon Heung Bae¹,Ploypradith Poonsakdi¹,Paik Ik-Hyeon¹,Borstnik Kristina¹,Xie Suji¹,Shapiro Theresa A.¹

Affiliation:

1. Department of Chemistry, School of Arts and Sciences, The Johns Hopkins University, 3400 N. Charles Street, Baltimore, Maryland 21218-2685, Division of Clinical Pharmacology, Department of Medicine, School of Medicine, The Johns Hopkins University, Baltimore, Maryland 21205, and Malaria Research Institute, Bloomberg School of Public Health, The Johns Hopkins University, Baltimore, Maryland 21205

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm020210h

Reference21 articles.

1. The Global Spread of Malaria in a Future, Warmer World

2. Qinghaosu (Artemisinin): an Antimalarial Drug from China

3. From Qinghao, Marvelous Herb of Antiquity, to the Antimalarial Trioxane Qinghaosuand Some Remarkable New Chemistry

4. Artemisinin and the antimalarial endoperoxides: from herbal remedy to targeted chemotherapy

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